AgF-mediated fluorinative homocoupling of gem-difluoroalkenes.

نویسندگان

  • Bing Gao
  • Yanchuan Zhao
  • Chuanfa Ni
  • Jinbo Hu
چکیده

A novel silver(I)-fluoride-mediated homocoupling reaction of β,β-difluorostyrene derivatives is described. The transformation is initiated via nucleophilic addition of silver(I) fluoride to β,β-difluorostyrenes, which is followed by dimerization of the corresponding benzylsilver intermediates. The reaction shows good substrate scope, functional group tolerance, and represents the first report on the reactivity of (α-trifluoromethyl)benzylsilver species.

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عنوان ژورنال:
  • Organic letters

دوره 16 1  شماره 

صفحات  -

تاریخ انتشار 2014